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Advances in genetic science have transformed the medical community’s understanding of inherited diseases, and few innovations have generated as much attention as CRISPR gene-editing technology. As researchers continue to explore new methods for treating genetic disorders, CRISPR has emerged as one of the most promising scientific developments of the 21st century. By enabling scientists to make highly precise modifications to DNA, CRISPR has the potential to reshape the future

Growth disorders caused by excess growth hormone offer a compelling look at how timing and genetics influence human development. Two closely related conditions, gigantism and acromegaly, arise from similar biological mechanisms but present very differently depending on when hormone imbalance occurs. Gigantism develops during childhood or adolescence, before the closure of the epiphyseal growth plates. In this stage of development, excess growth hormone leads to accelerated li

Glioblastoma, also known as GBM, is an aggressive and fast-growing form of brain cancer that develops in the brain or spinal cord. It often presents with symptoms like persistent headaches, memory issues, confusion, or difficulty with movement and speech. Because these symptoms can be subtle at first or mistaken for less serious conditions, many individuals are not diagnosed until the tumor has already progressed significantly. Glioblastoma forms from astrocytes, which are ce

Huntington’s disease is a genetic disorder that causes nerve cells to gradually break down and die. This disease is very rare, affecting about five in every 100,000 people in the United States. A mutation in the HTT gene causes it to fold incorrectly and clump together. These clumps over time begin to damage the brain cells. Huntington’s disease follows a dominant inheritance pattern which means that only one mutated copy of the HTT gene is needed to express the effected phen

Sickle Cell Disease Sickle cell disease is a genetic disorder that directly impacts about 100,000 Americans today. It is the most common inherited blood disorder in the United States. Sickle Cell disease causes red blood cells to form in the shape of a “c” instead of their normal round shape. Sickle Cell disease is caused by a point mutation in the Hemoglobin-Beta (HBB) gene on chromosome 11 of the genome. The HBB gene has instructions for making hemoglobin, which is the par

Hereditary Pancreatitis is a genetic condition that causes painful inflammation of the pancreas. It presents itself as abdominal pain and is often indistinguishable from any other causes, which leads many who do have hereditary pancreatitis to go undiagnosed and untreated for years. Hereditary Pancreatitis is a genetic condition caused by the mutations of either the R122H or N291 genes (sometimes other genes, but typically one of these two). When comparing patients with the